What Selank is
Selank is a synthetic seven-residue peptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro. Its first four residues reproduce tuftsin (Thr-Lys-Pro-Arg), a short peptide fragment of the immunoglobulin G heavy chain, and the C-terminal Pro-Gly-Pro extension was added to make the sequence more resistant to peptidase cleavage. Three of its seven residues are proline, which gives the molecule a rigid, extended backbone, and its two basic residues (lysine and arginine) make it strongly cationic at neutral pH.
Selank Labs supplies Selank as a lyophilized powder in 10 mg vials. Each lot is tested by an independent laboratory for HPLC-UV purity, LC-MS identity and net content, and the full certificate is published here before the material is sold through Klow.bio.
Structure
Selank is linear, with a free N-terminal amine and a free C-terminal carboxylic acid. It has no cysteine, methionine or tryptophan, so it carries none of the residues most prone to oxidation. Lysine 2 and arginine 4 are the only charged side chains.
complete Selank specifications.
Storage and handling
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.